Management of cardiovascular diseases in cancer patients is complex and challenging (1,2). Patients with cancer are at increased risk of cardiac diseases due to the shared cardiovascular risk factors, cardiovascular toxicity of cancer therapy, along with the proinflammatory and prothrombotic state caused by cancer (3–5). Stratification of the risk of bleeding and thrombosis in cancer patients can be a dilemma to health professionals as the traditional risk scores are not validated in cancer patients (2,6). In order to help professionals adopt the best management approach for cancer patients, the European Society of Cardiology (ESC) published the long-awaited first ESC Guidelines on cardio- oncology (7). The guidelines provide recommendations regarding diagnosis and management of acute and subacute cardiovascular toxicity in patients receiving anticancer treatment, and prevention and monitoring of cardiovascular complications during cancer therapy. The present editorial focuses on the key messages for prevention of bleeding and thromboembolic events in cancer patients from the first ESC cardio-oncology guidelines that can be frequently encountered during daily acute cardiovascular care particularly in patients presenting with acute coronary syndrome (ACS) and atrial fibrillation (AF).

Authors Heartbeat Sub-Editor: Sandeep Singh Dr Sandeep Singh is a Cardiology Clinical Fellow at Nottingham University Hospitals NHS Trust. After graduating from India, he completed

Authors Heartbeat Sub-Editor: Khin Kay Kay Kyaw I am currently working as cardiology specialist registrar ST6 at southwest peninsula region while also working as an

Authors Heartbeat Sub-Editor: Anindya Mukherjee Dr. Anindya Mukherjee is a ST5 trainee registrar in Cardiology at Mid Yorkshire Teaching NHS Trust, UK, with extensive experience

Authors Sub-editor: Sameer Zaman Heartbeat Sub-Editor: Aleena Haider Aleena is an academic cardiology trainee at Imperial College London with a strong commitment to all aspects

Authors Sub-editor: Sameer Zaman Heartbeat Sub-Editor: Padraig O Drisceoil Dr Pádraig Ó Drisceoil is a Cardiology Speciality Trainee from the Wessex Deanery, who is currently an