Polygenic risk scores in cardiovascular disease: are they ready for clinical use?

Home » BCS Editorials » Polygenic risk scores in cardiovascular disease: are they ready for clinical use?

Dr Vijay Shyam Sundar

17/12/2024

Take home messages

Cardiovascular disease risk tools remain imprecise. It remains unclear how to integrate polygenic risk scores with these tools.
Integrated risk tools have been evaluated in primary care combining genetic risk with other clinical data.
Polygenic risk scores can enhance cardiovascular disease risk stratification with the potential to impact on preventive therapy.
Further prospective studies of polygenic risk scores and the impact on preventive medications and risk reduction are required.